An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies

Hasselluhn MC, Schlosser D, Versemann L, et al. An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies (PMID: 37913894). Gastroenterology. 2024.

Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation

Godfrey LK, Forster J, Liffers ST, et al. Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation (PMID: 38229153). Clin Epigenetics. 2024.

TROP2 in colorectal carcinoma: associations with histopathology, molecular phenotype, and patient prognosis

Foersch S, Schmitt M, Litmeyer AS, et al. TROP2 in colorectal carcinoma: associations with histopathology, molecular phenotype, and patient prognosis (PMID: 39177576). J Pathol Clin Res. 2024.

High CIB1 expression in colorectal cancer liver metastases correlates with worse survival and the replacement histopathological growth pattern

Fan S, Fleischer JR, Dokshokova L, et al. High CIB1 expression in colorectal cancer liver metastases correlates with worse survival and the replacement histopathological growth pattern (PMID: 39072289). Mol Ther Oncol. 2024.

Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response

An J, Kurilov R, Peccerella T, et al. Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response (PMID: 39217851). Transl Oncol. Epub 2024.

Is this what the future of cancer research looks like?

Cancer: Researchers search for reasons for therapy resistance

Mamma Mia! Explanatory videos on CATCH / COGNITION

Interview Andreas Trumpp: Overcoming resistance (Einblick – The Journal of the German Cancer Research Center)

FutureXChange – The Future Forum of the National Decade Against Cancer Project pitch SATURN3 by Jens Siveke