Schneider C, Hilbert J, Genevaux F, et al. A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction (PMID: 38885414). Adv Sci (Weinh). 2024.
Author: Tassilo Steinmann
IL-2 and TCR stimulation induce expression and secretion of IL-32beta by human T cells
Sanna FC, Benesova I, Pervan P, et al. IL-2 and TCR stimulation induce expression and secretion of IL-32beta by human T cells (PMID: 39211051). Front Immunol. 2024.
An Analysis of PIK3CA Hotspot Mutations and Response to Neoadjuvant Therapy in Patients with Breast Cancer from Four Prospective Clinical Trials
Jank P, Karn T, van Mackelenbergh M, et al. An Analysis of PIK3CA Hotspot Mutations and Response to Neoadjuvant Therapy in Patients with Breast Cancer from Four Prospective Clinical Trials (PMID: 38837894). Clin Cancer Res. 2024.
An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies
Hasselluhn MC, Schlosser D, Versemann L, et al. An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies (PMID: 37913894). Gastroenterology. 2024.
Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation
Godfrey LK, Forster J, Liffers ST, et al. Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation (PMID: 38229153). Clin Epigenetics. 2024.
TROP2 in colorectal carcinoma: associations with histopathology, molecular phenotype, and patient prognosis
Foersch S, Schmitt M, Litmeyer AS, et al. TROP2 in colorectal carcinoma: associations with histopathology, molecular phenotype, and patient prognosis (PMID: 39177576). J Pathol Clin Res. 2024.
High CIB1 expression in colorectal cancer liver metastases correlates with worse survival and the replacement histopathological growth pattern
Fan S, Fleischer JR, Dokshokova L, et al. High CIB1 expression in colorectal cancer liver metastases correlates with worse survival and the replacement histopathological growth pattern (PMID: 39072289). Mol Ther Oncol. 2024.
Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response
An J, Kurilov R, Peccerella T, et al. Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response (PMID: 39217851). Transl Oncol. Epub 2024.