At the end of June, the SATURN3 consortium came together in Siegburg for its 5th General Assembly Meeting & Retreat. Surrounded by the beautiful scenery of the Michaelsberg, partners from across the consortium spent two productive days sharing project results, exchanging ideas across disciplines, and planning the exciting final year of SATURN3. The agenda was packed… Continue reading 5th GA Meeting in Siegburg highlights project progress and collaboration
Author: Tassilo Steinmann
Enhancing sensitivity and versatility of Tn5-based single cell omics.
Seufert I, Sant P, Bauer K, Syed AP, Rippe K and Mallm J-P. Enhancing sensitivity and versatility of Tn5-based single cell omics. Front. Epigenet. Epigenom. 2023 (doi: 10.3389/freae.2023.1245879)
Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time
Wittenzellner K, Lengl M, Reichert M. et al. Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time. JCI Insight. 2025 (PMID: 40424076).
Current and emerging concepts for systemic treatment of metastatic colorectal cancer.
Steup C, Kennel KB, Neurath MF, Fichtner-Feigl S, Greten FR. Current and emerging concepts for systemic treatment of metastatic colorectal cancer. Gut. 2025 (PMID: 41047178)
Comparison of spatial transcriptomics technologies using tumor cryosections.
Rademacher A, Huseynov A, Bortolomeazzi M, et al. Comparison of spatial transcriptomics technologies using tumor cryosections. Genome Biol. 2025 (PMID: 40542418)
COGNITION-GUIDE – Genomics-Guided Targeted Post-Neoadjuvant Therapy in Patients with Early Breast Cancer: Study Design of a Multicenter, Open-Label, Umbrella Phase II Study.
Pixberg C, Maurer C, Zapatka M, Erben V, Schumacher-Wulf E, Thewes V, Lichter P, Schneeweiss A. COGNITION-GUIDE – Genomics-Guided Targeted Post-Neoadjuvant Therapy in Patients with Early Breast Cancer: Study Design of a Multicenter, Open-Label, Umbrella Phase II Study. Geburtshilfe Frauenheilkd. 2025 (PMID: 40510401)
An immune responsive tumor microenvironment imprints into PBMCs and predicts outcome in advanced pancreatic cancer: lessons from the PREDICT trial.
Lahusen A, Lutz MP, Siveke JT, et al. An immune responsive tumor microenvironment imprints into PBMCs and predicts outcome in advanced pancreatic cancer: lessons from the PREDICT trial. Mol Cancer. 2025 (PMID: 40696453)
Detecting and quantifying clonal selection in somatic stem cells.
Körber V, Jakobsen NA, Ansari-Pour N. et al. Detecting and quantifying clonal selection in somatic stem cells. Nat Genet. 2025 (PMID: 40610627)
The immune microenvironment of colorectal cancer.
Kennel KB, Greten FR. The immune microenvironment of colorectal cancer. Nat Rev Cancer. 2025 (PMID: 40983666).
Large vesicles from ageing neutrophils: novel safeguards for the resolution of inflammation.
Dietz-Fricke C, Greten FR et al. Large vesicles from ageing neutrophils: novel safeguards for the resolution of inflammation. Signal Transduct Target Ther. 2025 (PMID: 40383810)