Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution

Fleischer JR, Schmitt AM, Haas G, et al. Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution (PMID: 36691028). Mol Cancer. 2023.

Colorectal Cancer Organoid-Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses

Farin HF, Mosa MH, Ndreshkjana B, et al. Colorectal Cancer Organoid-Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses (PMID: 37489084). Cancer Discov. 2023.

KRASG 12C-inhibitor-based combination therapies for pancreatic cancer: insights from drug screening

Tapia Contreras C, Falke JD, Seifert DM, et al. KRASG 12C-inhibitor-based combination therapies for pancreatic cancer: insights from drug screening. doi: 10.1002/1878-0261.13725. Mol Oncol. 2024 Online ahead of print.

A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction

Schneider C, Hilbert J, Genevaux F, et al. A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction (PMID: 38885414). Adv Sci (Weinh). 2024.

IL-2 and TCR stimulation induce expression and secretion of IL-32beta by human T cells

Sanna FC, Benesova I, Pervan P, et al. IL-2 and TCR stimulation induce expression and secretion of IL-32beta by human T cells (PMID: 39211051). Front Immunol. 2024.

Comparison of spatial transcriptomics technologies using tumor cryosections

Rademacher A, Huseynov A, Bortolomeazzi M, et al. Comparison of spatial transcriptomics technologies using tumor cryosections. bioRxiv. 2024.

Minimally invasive determination of pancreatic ductal adenocarcinoma (PDAC) subtype by means of circulating cell-free RNA

Metzenmacher M, Zaun G, Trajkovic-Arsic M et al. Minimally invasive determination of pancreatic ductal adenocarcinoma (PDAC) subtype by means of circulating cell-free RNA (PMID: 39478658). Mol Oncol. 2024. Online ahead of print.

An Analysis of PIK3CA Hotspot Mutations and Response to Neoadjuvant Therapy in Patients with Breast Cancer from Four Prospective Clinical Trials

Jank P, Karn T, van Mackelenbergh M, et al. An Analysis of PIK3CA Hotspot Mutations and Response to Neoadjuvant Therapy in Patients with Breast Cancer from Four Prospective Clinical Trials (PMID: 38837894). Clin Cancer Res. 2024.

An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies

Hasselluhn MC, Schlosser D, Versemann L, et al. An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies (PMID: 37913894). Gastroenterology. 2024.

Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation

Godfrey LK, Forster J, Liffers ST, et al. Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation (PMID: 38229153). Clin Epigenetics. 2024.