Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution

Fleischer JR, Schmitt AM, Haas G, et al. Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution (PMID: 36691028). Mol Cancer. 2023.

Colorectal Cancer Organoid-Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses

Farin HF, Mosa MH, Ndreshkjana B, et al. Colorectal Cancer Organoid-Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses (PMID: 37489084). Cancer Discov. 2023.

A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction

Schneider C, Hilbert J, Genevaux F, et al. A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction (PMID: 38885414). Adv Sci (Weinh). 2024.

IL-2 and TCR stimulation induce expression and secretion of IL-32beta by human T cells

Sanna FC, Benesova I, Pervan P, et al. IL-2 and TCR stimulation induce expression and secretion of IL-32beta by human T cells (PMID: 39211051). Front Immunol. 2024.

Comparison of spatial transcriptomics technologies using tumor cryosections

Rademacher A, Huseynov A, Bortolomeazzi M, et al. Comparison of spatial transcriptomics technologies using tumor cryosections. bioRxiv. 2024.

An Analysis of PIK3CA Hotspot Mutations and Response to Neoadjuvant Therapy in Patients with Breast Cancer from Four Prospective Clinical Trials

Jank P, Karn T, van Mackelenbergh M, et al. An Analysis of PIK3CA Hotspot Mutations and Response to Neoadjuvant Therapy in Patients with Breast Cancer from Four Prospective Clinical Trials (PMID: 38837894). Clin Cancer Res. 2024.

An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies

Hasselluhn MC, Schlosser D, Versemann L, et al. An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies (PMID: 37913894). Gastroenterology. 2024.

Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation

Godfrey LK, Forster J, Liffers ST, et al. Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation (PMID: 38229153). Clin Epigenetics. 2024.

TROP2 in colorectal carcinoma: associations with histopathology, molecular phenotype, and patient prognosis

Foersch S, Schmitt M, Litmeyer AS, et al. TROP2 in colorectal carcinoma: associations with histopathology, molecular phenotype, and patient prognosis (PMID: 39177576). J Pathol Clin Res. 2024.

High CIB1 expression in colorectal cancer liver metastases correlates with worse survival and the replacement histopathological growth pattern

Fan S, Fleischer JR, Dokshokova L, et al. High CIB1 expression in colorectal cancer liver metastases correlates with worse survival and the replacement histopathological growth pattern (PMID: 39072289). Mol Ther Oncol. 2024.