KRASG 12C-inhibitor-based combination therapies for pancreatic cancer: insights from drug screening

Tapia Contreras C, Falke JD, Seifert DM, et al. KRAS(G) (12C)-inhibitor-based combination therapies for pancreatic cancer: insights from drug screening (PMID: 39253995). Mol Oncol. 2025.

Characterization of single neurons reprogrammed by pancreatic cancer

Thiel V, Renders S, Panten J, et al. Characterization of single neurons reprogrammed by pancreatic cancer (PMID: 39961335). Nature. 2025.

Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1-HER3 signaling

Wurth R, Donato E, Michel LL, et al. Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1-HER3 signaling (PMID: 39753722). Nat Cancer. 2025.

PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma

Zhao B, Fang R, Schurmann H, et al. PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma (PMID: 40188436). Cell Rep. 2025.

Multimodal survival prediction in advanced pancreatic cancer using machine learning

Keyl J, Kasper S, Wiesweg M, et al. Multimodal survival prediction in advanced pancreatic cancer using machine learning (PMID: 35988455). ESMO Open. Epub 2022.

Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma

Heid I, Münch C, Karakaya S, et al. Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma (PMID: 36494842). Cancer Metab. 2022.

HAPLN1 potentiates peritoneal metastasis in pancreatic cancer

Wiedmann L, De Angelis Rigotti F, Vaquero-Siguero N, et al. HAPLN1 potentiates peritoneal metastasis in pancreatic cancer (PMID: 37095087). Nat Commun. 2023.

Approaches for single-cell RNA sequencing across tissues and cell types

Sant P, Rippe K and Mallm JP. Approaches for single-cell RNA sequencing across tissues and cell types (PMID: 37062951). Transcription. 2023.

Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer

Saini M, Schmidleitner L, Moreno HD, et al. Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer (PMID: 37257449). Cell Rep. Epub 2023.

Smaller panel, similar results: genomic profiling and molecularly informed therapy in pancreatic cancer

Reissig TM, Tzianopoulos I, Liffers ST, et al. Smaller panel, similar results: genomic profiling and molecularly informed therapy in pancreatic cancer (PMID: 37148593). ESMO Open. Epub 2023.